Suppression of InsP(3) Receptor-Mediated Ca(2+) Signaling Alleviates Mutant Presenilin-Linked Familial Alzheimer's Disease Pathogenesis

Exaggerated intracellular Ca(2+) signaling is a robust proximal phenotype observed in cells expressing familial Alzheimer's disease (FAD)-causing mutant presenilins (PSs). The mechanisms that underlie this phenotype are controversial and their in vivo relevance for AD pathogenesis is unknown. H...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shilling, Dustin, Müller, Marioly, Takano, Hajime, Daniel Mak, Don-On, Abel, Ted, Coulter, Douglas A., Foskett, J. Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019804/
https://ncbi.nlm.nih.gov/pubmed/24828645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5441-13.2014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados