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Structure of a Eukaryotic RNase III Post-Cleavage Complex Reveals a Double- Ruler Mechanism for Substrate Selection
RNase III represents a family of dsRNA-specific endoribonucleases required for RNA maturation and gene regulation. The mechanism of action has been well characterized for the bacterial enzyme, but is not clear for eukaryotic RNase IIIs. Here, we describe the structure of Saccharomyces cerevisiae RNa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019767/ https://ncbi.nlm.nih.gov/pubmed/24703949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.03.006 |
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