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Structure of a Eukaryotic RNase III Post-Cleavage Complex Reveals a Double- Ruler Mechanism for Substrate Selection

RNase III represents a family of dsRNA-specific endoribonucleases required for RNA maturation and gene regulation. The mechanism of action has been well characterized for the bacterial enzyme, but is not clear for eukaryotic RNase IIIs. Here, we describe the structure of Saccharomyces cerevisiae RNa...

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Bibliografski detalji
Glavni autori: Liang, Yu-He, Lavoie, Mathieu, Comeau, Marc-Andre, Elela, Sherif Abou, Ji, Xinhua
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019767/
https://ncbi.nlm.nih.gov/pubmed/24703949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.03.006
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