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Structure of a Eukaryotic RNase III Post-Cleavage Complex Reveals a Double- Ruler Mechanism for Substrate Selection

RNase III represents a family of dsRNA-specific endoribonucleases required for RNA maturation and gene regulation. The mechanism of action has been well characterized for the bacterial enzyme, but is not clear for eukaryotic RNase IIIs. Here, we describe the structure of Saccharomyces cerevisiae RNa...

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Bibliografiska uppgifter
Huvudupphovsmän: Liang, Yu-He, Lavoie, Mathieu, Comeau, Marc-Andre, Elela, Sherif Abou, Ji, Xinhua
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019767/
https://ncbi.nlm.nih.gov/pubmed/24703949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.03.006
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