The catalytic efficiency of yeast ribonuclease III depends on substrate specific product release rate

Members of the ribonuclease III (RNase III) family regulate gene expression by triggering the degradation of double stranded RNA (dsRNA). Hundreds of RNase III cleavage targets have been identified and their impact on RNA maturation and stability is now established. However, the mechanism defining s...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Comeau, Marc-Andre, Lafontaine, Daniel A., Abou Elela, Sherif
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027489/
https://ncbi.nlm.nih.gov/pubmed/27257067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw507
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