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KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps
The functional properties of KCNQ1 channels are highly dependent on associated KCNE β subunits. Mutations in KCNQ1 or KCNE subunits can cause congenital channelopathies, such as deafness, cardiac arrhythmias, and epilepsy. The mechanism by which KCNE1 beta subunits slow the kinetics of KCNQ1 channel...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019390/ https://ncbi.nlm.nih.gov/pubmed/24769622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4750 |
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