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Cleft Palate in a Mouse Model of SOX2 Haploinsufficiency

OBJECTIVE: While SEX-determining region Y-Box 2 (SOX2) mutations are typically recognized as yielding ocular and central nervous system abnormalities, they have also been associated with other craniofacial defects. To elucidate the genesis of the latter, Sox2 hypomorphic (Sox2(HYP)) mice were examin...

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Autori principali: Langer, Lee, Sulik, Kathleen, Pevny, Larysa
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019342/
https://ncbi.nlm.nih.gov/pubmed/23638914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1597/12-260
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