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Cleft Palate in a Mouse Model of SOX2 Haploinsufficiency

OBJECTIVE: While SEX-determining region Y-Box 2 (SOX2) mutations are typically recognized as yielding ocular and central nervous system abnormalities, they have also been associated with other craniofacial defects. To elucidate the genesis of the latter, Sox2 hypomorphic (Sox2(HYP)) mice were examin...

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Main Authors: Langer, Lee, Sulik, Kathleen, Pevny, Larysa
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019342/
https://ncbi.nlm.nih.gov/pubmed/23638914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1597/12-260
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