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Cleft Palate in a Mouse Model of SOX2 Haploinsufficiency

OBJECTIVE: While SEX-determining region Y-Box 2 (SOX2) mutations are typically recognized as yielding ocular and central nervous system abnormalities, they have also been associated with other craniofacial defects. To elucidate the genesis of the latter, Sox2 hypomorphic (Sox2(HYP)) mice were examin...

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Détails bibliographiques
Auteurs principaux: Langer, Lee, Sulik, Kathleen, Pevny, Larysa
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019342/
https://ncbi.nlm.nih.gov/pubmed/23638914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1597/12-260
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