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Sox2 haploinsufficiency primes regeneration and Wnt responsiveness in the mouse cochlea
During development, Sox2 is indispensable for cell division and differentiation, yet its roles in regenerating tissues are less clear. Here, we used combinations of transgenic mouse models to reveal that Sox2 haploinsufficiency (Sox2(haplo)) increases rather than impairs cochlear regeneration in viv...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5873847/ https://ncbi.nlm.nih.gov/pubmed/29553487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97248 |
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