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Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea
Planar cell polarity (PCP) proteins localize asymmetrically to instruct cell polarity within the tissue plane, with defects leading to deformities of the limbs, neural tube and inner ear. Wnt proteins are evolutionarily conserved polarity cues, yet Wnt mutants display variable PCP defects; thus, how...
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| Veröffentlicht in: | Development |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7561480/ https://ncbi.nlm.nih.gov/pubmed/32907846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.191981 |
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