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Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo
The planar cell polarity (PCP; non-canonical Wnt) pathway is required to orient the cells within the plane of an epithelium. Here, we show that cofilin 1 (Cfl1), an actin-severing protein, and Vangl2, a core PCP protein, cooperate to control PCP in the early mouse embryo. Two aspects of planar polar...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585660/ https://ncbi.nlm.nih.gov/pubmed/23406901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.085316 |
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