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Depletion of the cdk Inhibitor p16(INK4a) Differentially Affects Proliferation of Established Cervical Carcinoma Cells

Infections with high-risk human papillomaviruses (hrHPV) contribute to cervical carcinoma. The cdk inhibitor and tumor suppressor p16(INK4A) is consistently upregulated in cervical carcinoma cells for reasons that are poorly understood. We report here that downregulation of p16(INK4A) gene expressio...

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Bibliografiske detaljer
Main Authors: Pauck, Alexander, Lener, Barbara, Hoell, Monika, Kaiser, Andreas, Kaufmann, Andreas M., Zwerschke, Werner, Jansen-Dürr, Pidder
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019144/
https://ncbi.nlm.nih.gov/pubmed/24599991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03817-13
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