The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1

We demonstrate that HPV-16 E7 forms a complex with Miz-1. UV-induced expression of the CDK-inhibitor p21(Cip1) and subsequent cell cycle arrest depends upon endogenous Miz-1 in HPV-negative C33A cervical cancer cells containing mutated p53. Transient expression of E7 in C33A inhibits UV-induced expr...

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Huvudupphovsmän: Morandell, Dieter, Kaiser, Andreas, Herold, Steffi, Rostek, Ursula, Lechner, Stefan, Mitterberger, Maria C., Jansen-Dürr, Pidder, Eilers, Martin, Zwerschke, Werner
Materialtyp: Artigo
Språk:Inglês
Publicerad: Academic Press 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268862/
https://ncbi.nlm.nih.gov/pubmed/22099967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.10.027
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