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Depletion of the cdk Inhibitor p16(INK4a) Differentially Affects Proliferation of Established Cervical Carcinoma Cells

Infections with high-risk human papillomaviruses (hrHPV) contribute to cervical carcinoma. The cdk inhibitor and tumor suppressor p16(INK4A) is consistently upregulated in cervical carcinoma cells for reasons that are poorly understood. We report here that downregulation of p16(INK4A) gene expressio...

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Autors principals: Pauck, Alexander, Lener, Barbara, Hoell, Monika, Kaiser, Andreas, Kaufmann, Andreas M., Zwerschke, Werner, Jansen-Dürr, Pidder
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019144/
https://ncbi.nlm.nih.gov/pubmed/24599991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03817-13
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