Functional Evidence for the Involvement of Microtubules and Dynein Motor Complexes in TRIM5α-Mediated Restriction of Retroviruses

The tripartite motif (TRIM) family of proteins includes the TRIM5α antiretroviral restriction factor. TRIM5α from many Old World and some New World monkeys can restrict the human immunodeficiency virus type 1 (HIV-1), while human TRIM5α restricts N-tropic murine leukemia virus (N-MLV). TRIM5α forms...

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Detalhes bibliográficos
Main Authors: Pawlica, Paulina, Le Sage, Valerie, Poccardi, Nolwenn, Tremblay, Michel J., Mouland, Andrew J., Berthoux, Lionel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019117/
https://ncbi.nlm.nih.gov/pubmed/24600008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03717-13
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