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Virus-Specific Effects of TRIM5α(rh) RING Domain Functions on Restriction of Retroviruses
The tripartite motif protein TRIM5α restricts particular retrovirus infections by binding to the incoming capsid and inhibiting the early stage of virus infection. The TRIM5α RING domain exhibits E3 ubiquitin ligase activity and assists the higher-order association of TRIM5α dimers, which promotes c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700309/ https://ncbi.nlm.nih.gov/pubmed/23637418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00620-13 |
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