Signal Integration and Gene Induction by a Functionally Distinct STAT3 Phosphoform

Aberrant activation of the ubiquitous transcription factor STAT3 is a major driver of solid tumor progression and pathological angiogenesis. STAT3 activity is regulated by numerous posttranslational modifications (PTMs), including Tyr(705) phosphorylation, which is widely used as an indicator of can...

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Detalhes bibliográficos
Principais autores: Waitkus, Matthew S., Chandrasekharan, Unni M., Willard, Belinda, Tee, Thomas L., Hsieh, Jason K., Przybycin, Christopher G., Rini, Brian I., DiCorleto, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019034/
https://ncbi.nlm.nih.gov/pubmed/24615012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00034-14
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