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N(pro) of classical swine fever virus contributes to pathogenicity in pigs by preventing type I interferon induction at local replication sites
Classical swine fever (CSF) caused by CSF virus (CSFV) is a highly contagious disease of pigs. The viral protein N(pro) of CSFV interferes with alpha- and beta-interferon (IFN-α/β) induction by promoting the degradation of interferon regulatory factor 3 (IRF3). During the establishment of the live a...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018971/ https://ncbi.nlm.nih.gov/pubmed/24742209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-45-47 |
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