Selection of Classical Swine Fever Virus with Enhanced Pathogenicity Reveals Synergistic Virulence Determinants in E2 and NS4B

Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), a highly contagious disease of pigs. There are numerous CSFV strains that differ in virulence, resulting in clinical disease with different degrees of severity. Low-virulent and moderately virulent isolates cau...

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Bibliographic Details
Main Authors: Tamura, Tomokazu, Sakoda, Yoshihiro, Yoshino, Fumi, Nomura, Takushi, Yamamoto, Naoki, Sato, Yuka, Okamatsu, Masatoshi, Ruggli, Nicolas, Kida, Hiroshi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421723/
https://ncbi.nlm.nih.gov/pubmed/22674973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00551-12
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