Selection of Classical Swine Fever Virus with Enhanced Pathogenicity Reveals Synergistic Virulence Determinants in E2 and NS4B

Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), a highly contagious disease of pigs. There are numerous CSFV strains that differ in virulence, resulting in clinical disease with different degrees of severity. Low-virulent and moderately virulent isolates cau...

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Main Authors: Tamura, Tomokazu, Sakoda, Yoshihiro, Yoshino, Fumi, Nomura, Takushi, Yamamoto, Naoki, Sato, Yuka, Okamatsu, Masatoshi, Ruggli, Nicolas, Kida, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421723/
https://ncbi.nlm.nih.gov/pubmed/22674973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00551-12
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