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Enhancing Resistance to Cephalosporins in class C β-lactamases: impact of Glu214Gly in CMY-2
The biochemical properties of CMY-32, a class C enzyme possessing a single amino acid substitution in the Ω loop (Gly214Glu) were compared to the parent enzyme, CMY-2, a widespread class C β-lactamase. In parallel with our microbiological characterization, the Gly214Glu substitution in CMY-32 reduce...
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Κύριοι συγγραφείς: | , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2010
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018810/ https://ncbi.nlm.nih.gov/pubmed/19938877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9015549 |
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