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Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-β

Transforming growth factor β (TGF-β) isoforms are secreted as inactive complexes formed through noncovalent interactions between the bioactive TGF-β entity and its N-terminal latency-associated peptide prodomain. Extracellular activation of the latent TGF-β complex is a crucial step in the regulatio...

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Bibliographic Details
Main Authors: Alcaraz, Lindsay B., Exposito, Jean-Yves, Chuvin, Nicolas, Pommier, Roxane M., Cluzel, Caroline, Martel, Sylvie, Sentis, Stéphanie, Bartholin, Laurent, Lethias, Claire, Valcourt, Ulrich
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018787/
https://ncbi.nlm.nih.gov/pubmed/24821840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201308031
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