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Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-β
Transforming growth factor β (TGF-β) isoforms are secreted as inactive complexes formed through noncovalent interactions between the bioactive TGF-β entity and its N-terminal latency-associated peptide prodomain. Extracellular activation of the latent TGF-β complex is a crucial step in the regulatio...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018787/ https://ncbi.nlm.nih.gov/pubmed/24821840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201308031 |
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