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Latent TGF-β Activation Is a Hallmark of the Tenascin Family
Transforming growth factor-β (TGF-β) isoforms are secreted as inactive complexes formed through non-covalent interactions between bioactive TGF-β entities and their N-terminal pro-domains called latency-associated peptides (LAP). Extracellular activation of latent TGF-β within this complex is a cruc...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8155481/ https://ncbi.nlm.nih.gov/pubmed/34054795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.613438 |
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