OX(1) and OX(2) orexin/hypocretin receptor pharmacogenetics

Orexin/hypocretin peptide mutations are rare in humans. Even though human narcolepsy is associated with orexin deficiency, this is only extremely rarely due to mutations in the gene coding prepro-orexin, the precursor for both orexin peptides. In contrast, coding and non-coding variants of the OX(1)...

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Hlavní autoři: Thompson, Miles D., Xhaard, Henri, Sakurai, Takeshi, Rainero, Innocenzo, Kukkonen, Jyrki P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018553/
https://ncbi.nlm.nih.gov/pubmed/24834023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00057
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