Genetic Association Study of Adiposity and Melanocortin-4 Receptor (MC4R) Common Variants: Replication and Functional Characterization of Non-Coding Regions

Common genetic variants 3′ of MC4R within two large linkage disequilibrium (LD) blocks spanning 288 kb have been associated with common and rare forms of obesity. This large association region has not been refined and the relevant DNA segments within the association region have not been identified....

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Autori principali: Evans, Daniel S., Calton, Melissa A., Kim, Mee J., Kwok, Pui-Yan, Miljkovic, Iva, Harris, Tamara, Koster, Annemarie, Liu, Yongmei, Tranah, Gregory J., Ahituv, Nadav, Hsueh, Wen-Chi, Vaisse, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018404/
https://ncbi.nlm.nih.gov/pubmed/24820477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096805
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