Genetic Association Study of Adiposity and Melanocortin-4 Receptor (MC4R) Common Variants: Replication and Functional Characterization of Non-Coding Regions

Common genetic variants 3′ of MC4R within two large linkage disequilibrium (LD) blocks spanning 288 kb have been associated with common and rare forms of obesity. This large association region has not been refined and the relevant DNA segments within the association region have not been identified....

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Detalhes bibliográficos
Main Authors: Evans, Daniel S., Calton, Melissa A., Kim, Mee J., Kwok, Pui-Yan, Miljkovic, Iva, Harris, Tamara, Koster, Annemarie, Liu, Yongmei, Tranah, Gregory J., Ahituv, Nadav, Hsueh, Wen-Chi, Vaisse, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018404/
https://ncbi.nlm.nih.gov/pubmed/24820477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096805
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