Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

OBJECTIVE: Pro-opiomelanocortin (POMC)-derived peptides act on neurons expressing the Melanocortin 4 receptor (MC4R) to reduce body weight. Setmelanotide is a highly potent MC4R agonist that leads to weight loss in diet-induced obese animals and in obese individuals with complete POMC deficiency. Wh...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mol Metab
Autors principals: Collet, Tinh-Hai, Dubern, Béatrice, Mokrosinski, Jacek, Connors, Hillori, Keogh, Julia M., Mendes de Oliveira, Edson, Henning, Elana, Poitou-Bernert, Christine, Oppert, Jean-Michel, Tounian, Patrick, Marchelli, Florence, Alili, Rohia, Le Beyec, Johanne, Pépin, Dominique, Lacorte, Jean-Marc, Gottesdiener, Andrew, Bounds, Rebecca, Sharma, Shubh, Folster, Cathy, Henderson, Bart, O'Rahilly, Stephen, Stoner, Elizabeth, Gottesdiener, Keith, Panaro, Brandon L., Cone, Roger D., Clément, Karine, Farooqi, I. Sadaf, Van der Ploeg, Lex H.T.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641599/
https://ncbi.nlm.nih.gov/pubmed/29031731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.06.015
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars