Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case–control study

Functionally significant heterozygous mutations in the Melanocortin-4 receptor (MC4R) have been implicated in 2.5% of early onset obesity cases in European cohorts. The role of mutations in this gene in severely obese adults, particularly in smaller North American patient cohorts, has been less conv...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Calton, Melissa A., Ersoy, Baran A., Zhang, Sumei, Kane, John P., Malloy, Mary J., Pullinger, Clive R., Bromberg, Yana, Pennacchio, Len A., Dent, Robert, McPherson, Ruth, Ahituv, Nadav, Vaisse, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Association Studies Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649015/
https://ncbi.nlm.nih.gov/pubmed/19091795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn431
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados