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Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain
Tapentadol is a dual action molecule with mu opioid agonist and norepinephrine (NE) reuptake blocking activity that has recently been introduced for the treatment of moderate to severe pain. The effects of intraperitoneal (i.p.) morphine (10 mg/kg), tapentadol (10 or 30 mg/kg) or duloxetine (30 mg/k...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018237/ https://ncbi.nlm.nih.gov/pubmed/23969300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.08.017 |
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