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Multiple sites and actions of gabapentin-induced relief of ongoing experimental neuropathic pain

Gabapentin is a first-line therapy for neuropathic pain but its mechanisms and sites of action remain uncertain. We investigated gabapentin-induced modulation of neuropathic pain following spinal nerve ligation (SNL) in rats. Intravenous or intrathecal gabapentin reversed evoked mechanical hypersens...

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Bibliografische gegevens
Gepubliceerd in:Pain
Hoofdauteurs: Bannister, Kirsty, Qu, Chaoling, Navratilova, Edita, Oyarzo, Janice, Xie, Jennifer Yanhua, King, Tamara, Dickenson, Anthony H., Porreca, Frank
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681862/
https://ncbi.nlm.nih.gov/pubmed/28832395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001040
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