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Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy

Preclinical assessment of pain has increasingly explored operant methods that may allow behavioral assessment of ongoing pain. In animals with incisional injury, peripheral nerve block produces conditioned place preference (CPP) and activates the mesolimbic dopaminergic reward pathway. We hypothesiz...

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書誌詳細
主要な著者: Xie, Jennifer Y., Qu, Chaoling, Patwardhan, Amol, Ossipov, Michael H., Navratilova, Edita, Becerra, Lino, Borsook, David, Porreca, Frank
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118589/
https://ncbi.nlm.nih.gov/pubmed/24861580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2014.05.018
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