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The effects of the β-agonist isoproterenol on the down-regulation, functional responsiveness, and trafficking of β(2)-adrenergic receptors with amino-terminal polymorphisms
The β(2)-adrenergic receptor (β(2)AR) is an important target for respiratory and cardiovascular disease medications. Clinical studies suggest that amino-terminal polymorphisms of the β(2)AR may act as disease modifiers. We hypothesized that polymorphisms at amino acids 16 and 27 result in differenti...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018189/ https://ncbi.nlm.nih.gov/pubmed/22938397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CBI20120134 |
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