Potent and Selective Inhibitors of Long Chain l-2-Hydroxy Acid Oxidase Reduced Blood Pressure in DOCA Salt-Treated Rats

[Image: see text] l-2-Hydroxy acid oxidase (Hao2) is a peroxisomal enzyme with predominant expression in the liver and kidney. Hao2 was recently identified as a candidate gene for blood pressure quantitative trait locus in rats. To investigate a pharmacological role of Hao2 in the management of bloo...

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主要な著者: Barawkar, Dinesh A., Meru, Ashwin, Bandyopadhyay, Anish, Banerjee, Abir, Deshpande, Anil M., Athare, Chandrashekhar, Koduru, Chandrasekhar, Khose, Goraksha, Gundu, Jayasagar, Mahajan, Koshu, Patil, Pradeep, Kandalkar, Sachin R., Niranjan, Sanjay, Bhosale, Shubhangi, De, Siddhartha, Mukhopadhyay, Sudit, Chaudhary, Sumit, Koul, Summon, Singh, Umesh, Chugh, Anita, Palle, Venkata P., Mookhtiar, Kasim A., Vacca, Joseph, Chakravarty, Prasun K., Nargund, Ravi P., Wright, Samuel D., Roy, Sophie, Graziano, Michael P., Singh, Sheo B., Cully, Doris, Cai, Tian-Quan
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2011
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018152/
https://ncbi.nlm.nih.gov/pubmed/24900281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2001938
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