Design, Synthesis, and Preclinical Characterization of the Selective Androgen Receptor Modulator (SARM) RAD140

[Image: see text] This report describes the discovery of RAD140, a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). The characterization of RAD140 in several preclinical models of anabolic androgen action is also described.

Na minha lista:
Detalhes bibliográficos
Main Authors: Miller, Chris P., Shomali, Maysoun, Lyttle, C. Richard, O’Dea, Louis St. L., Herendeen, Hillary, Gallacher, Kyla, Paquin, Dottie, Compton, Dennis R., Sahoo, Bishwabhusan, Kerrigan, Sean A., Burge, Matthew S., Nickels, Michael, Green, Jennifer L., Katzenellenbogen, John A., Tchesnokov, Alexei, Hattersley, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018048/
https://ncbi.nlm.nih.gov/pubmed/24900290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1002508
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados