RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models

Agents that inhibit estrogen production, such as aromatase inhibitors or those that directly block estrogen receptor (ER) activity, such as selective estrogen receptor modulators and selective estrogen receptor degraders, are routinely used in the treatment of ER-positive breast cancers. However, al...

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Detalhes bibliográficos
Publicado no:Anticancer Drugs
Main Authors: Garner, Fiona, Shomali, Maysoun, Paquin, Dotty, Lyttle, C. Richard, Hattersley, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Preclinical Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560273/
https://ncbi.nlm.nih.gov/pubmed/26164151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000271
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