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dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway
Axonal and synaptic degeneration is a hallmark of peripheral neuropathy, brain injury, and neurodegenerative disease. Axonal degeneration has been proposed to be mediated by an active autodestruction program, akin to apoptotic cell death; however, loss-of-function mutations capable of potently block...
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| Udgivet i: | Science |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225956/ https://ncbi.nlm.nih.gov/pubmed/22678360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1223899 |
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