Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

Glioblastoma multiforme (GBM) is a neurologically debilitating disease that culminates in death 14 to 16 months after diagnosis. An incomplete understanding of how cataloged genetic aberrations promote therapy resistance, combined with ineffective drug delivery to the central nervous system, has ren...

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Bibliografische gegevens
Hoofdauteurs: Jensen, Samuel A., Day, Emily S., Ko, Caroline H., Hurley, Lisa A., Luciano, Janina P., Kouri, Fotini M., Merkel, Timothy J., Luthi, Andrea J., Patel, Pinal C., Cutler, Joshua I., Daniel, Weston L., Scott, Alexander W., Rotz, Matthew W., Meade, Thomas J., Giljohann, David A., Mirkin, Chad A., Stegh, Alexander H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017940/
https://ncbi.nlm.nih.gov/pubmed/24174328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006839
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