Strained Cycloalkynes as New Protein Sulfenic Acid Traps

[Image: see text] Protein sulfenic acids are formed by the reaction of biologically relevant reactive oxygen species with protein thiols. Sulfenic acid formation modulates the function of enzymes and transcription factors either directly or through the subsequent formation of protein disulfide bonds...

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Bibliographic Details
Main Authors: Poole, Thomas H., Reisz, Julie A., Zhao, Weiling, Poole, Leslie B., Furdui, Cristina M., King, S. Bruce
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017607/
https://ncbi.nlm.nih.gov/pubmed/24724926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500364r
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