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Thiol-Blocking Electrophiles Interfere with Labeling and Detection of Protein Sulfenic Acids

Cellular exposure to reactive oxygen species induces the rapid oxidation of DNA, proteins, lipids, and other biomolecules. At the proteome level, cysteine thiol oxidation is a prominent post-translational process implicated in normal physiology and numerous pathologies. Methods for investigating pro...

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Autori principali: Reisz, Julie A., Bechtold, Erika, King, S. Bruce, Poole, Leslie B., Furdui, Cristina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928805/
https://ncbi.nlm.nih.gov/pubmed/24103186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12535
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