Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins()

Facile, two-step synthesis and kinetic characterization of new chemical probes for selective labeling of sulfenic acid (–SOH) in proteins are presented. The synthesis route relies on the simple and highly efficient Michael addition of thiol containing tags or linkers to 4-cyclopentene-1,3-dione, the...

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Hlavní autoři: Qian, Jiang, Klomsiri, Chananat, Wright, Marcus W., King, S. Bruce, Tsang, Allen W., Poole, Leslie B., Furdui, Cristina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587177/
https://ncbi.nlm.nih.gov/pubmed/21738918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc12127h
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