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Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins()

Facile, two-step synthesis and kinetic characterization of new chemical probes for selective labeling of sulfenic acid (–SOH) in proteins are presented. The synthesis route relies on the simple and highly efficient Michael addition of thiol containing tags or linkers to 4-cyclopentene-1,3-dione, the...

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Main Authors: Qian, Jiang, Klomsiri, Chananat, Wright, Marcus W., King, S. Bruce, Tsang, Allen W., Poole, Leslie B., Furdui, Cristina M.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587177/
https://ncbi.nlm.nih.gov/pubmed/21738918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc12127h
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