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A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes

β-ketoesters are robust probes for labeling sulfenic acid (−SOH) proteins allowing quantitative cleavage of the tag for improved analysis of the labeled peptides by MS.

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Bibliographic Details
Main Authors: Qian, Jiang, Wani, Revati, Klomsiri, Chananat, Poole, Leslie B., Tsang, Allen W., Furdui, Cristina M.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568515/
https://ncbi.nlm.nih.gov/pubmed/22430672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc17868k
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