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Strained Cycloalkynes as New Protein Sulfenic Acid Traps

[Image: see text] Protein sulfenic acids are formed by the reaction of biologically relevant reactive oxygen species with protein thiols. Sulfenic acid formation modulates the function of enzymes and transcription factors either directly or through the subsequent formation of protein disulfide bonds...

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Bibliografiske detaljer
Main Authors: Poole, Thomas H., Reisz, Julie A., Zhao, Weiling, Poole, Leslie B., Furdui, Cristina M., King, S. Bruce
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017607/
https://ncbi.nlm.nih.gov/pubmed/24724926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500364r
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