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Strained Cycloalkynes as New Protein Sulfenic Acid Traps

[Image: see text] Protein sulfenic acids are formed by the reaction of biologically relevant reactive oxygen species with protein thiols. Sulfenic acid formation modulates the function of enzymes and transcription factors either directly or through the subsequent formation of protein disulfide bonds...

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Detalhes bibliográficos
Main Authors: Poole, Thomas H., Reisz, Julie A., Zhao, Weiling, Poole, Leslie B., Furdui, Cristina M., King, S. Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017607/
https://ncbi.nlm.nih.gov/pubmed/24724926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500364r
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