Development and function of human innate immune cells in a humanized mouse model

Mice repopulated with human hematopoietic cells are a powerful tool for the study of human hematopoiesis and immune function in vivo. However, existing humanized mouse models are unable to support development of human innate immune cells, including myeloid cells and NK cells. Here we describe a mous...

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Detalhes bibliográficos
Main Authors: Rongvaux, Anthony, Willinger, Tim, Martinek, Jan, Strowig, Till, Gearty, Sofia V., Teichmann, Lino L., Saito, Yasuyuki, Marches, Florentina, Halene, Stephanie, Palucka, A. Karolina, Manz, Markus G., Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017589/
https://ncbi.nlm.nih.gov/pubmed/24633240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2858
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