IFNL4-ΔG Genotype Is Associated With Slower Viral Clearance in Hepatitis C, Genotype-1 Patients Treated With Sofosbuvir and Ribavirin

Response to pegylated interferon-alpha and ribavirin (IFN-α/RBV) treatment for chronic hepatitis C virus (HCV) infection is influenced by host genetic factors, but their role for IFN-α–free, direct-acting antiviral (DAA) regimens is unclear. An exonic deletion allele (IFNL4-ΔG) bolsters the establis...

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Hlavní autoři: Meissner, Eric G., Bon, Dimitra, Prokunina-Olsson, Ludmila, Tang, Wei, Masur, Henry, O'Brien, Thomas R., Herrmann, Eva, Kottilil, Shyamasundaran, Osinusi, Anuoluwapo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017364/
https://ncbi.nlm.nih.gov/pubmed/24367041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit827
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