Retreatment of HCV Genotype-1 with Sofosbuvir and Ledipasvir after Relapse with Sofosbuvir and Ribavirin: A Pilot Study

BACKGROUND: The interferon (IFN)-free regimen of sofosbuvir and ribavirin for 24 weeks was recently approved to treat chronic hepatitis C virus (HCV), genotype-1 (GT-1) infection for interferon-ineligible patients . However, sofosbuvir/ribavirin therapy is associated with treatment relapse in 15-30%...

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Detalhes bibliográficos
Publicado no:Ann Intern Med
Main Authors: Osinusi, Anu, Kohli, Anita, Marti, Miriam M, Nelson, Amy, Zhang, Xiaozhen, Meissner, Eric G, Silk, Rachel, Townsend, Kerry, Pang, Phillip S, Subramanian, Mani, McHutchison, John G., Fauci, Anthony S, Masur, Henry, Kottilil, Shyam
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586065/
https://ncbi.nlm.nih.gov/pubmed/25364884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/M14-1211
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