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Effect of Sofosbuvir and Ribavirin Treatment on Peripheral and Hepatic Lipid Metabolism in Chronic HCV, Genotype-1 Infected Patients

Hepatitis C virus (HCV) modulates intrahepatic cholesterol biosynthetic pathways to promote viral replication. Chronic HCV infection is associated with altered metabolism, including dyslipidemia and insulin resistance, which contributes to disease progression and influences response to therapy. To f...

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Détails bibliographiques
Publié dans:Hepatology
Auteurs principaux: Meissner, Eric G., Lee, Yu-Jin, Osinusi, Anu, Sims, Zayani, Qin, Jing, Sturdevant, Dan, McHutchison, John, Subramanian, Mani, Sampson, Maureen, Naggie, Susanna, Patel, Keyur, Remaley, Alan T., Masur, Henry, Kottilil, Shyam
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340816/
https://ncbi.nlm.nih.gov/pubmed/25203718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27424
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