Effect of Sofosbuvir and Ribavirin Treatment on Peripheral and Hepatic Lipid Metabolism in Chronic HCV, Genotype-1 Infected Patients

Hepatitis C virus (HCV) modulates intrahepatic cholesterol biosynthetic pathways to promote viral replication. Chronic HCV infection is associated with altered metabolism, including dyslipidemia and insulin resistance, which contributes to disease progression and influences response to therapy. To f...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Meissner, Eric G., Lee, Yu-Jin, Osinusi, Anu, Sims, Zayani, Qin, Jing, Sturdevant, Dan, McHutchison, John, Subramanian, Mani, Sampson, Maureen, Naggie, Susanna, Patel, Keyur, Remaley, Alan T., Masur, Henry, Kottilil, Shyam
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340816/
https://ncbi.nlm.nih.gov/pubmed/25203718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27424
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