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Crowding Activates ClpB and Enhances Its Association with DnaK for Efficient Protein Aggregate Reactivation

Reactivation of intracellular protein aggregates after a severe stress is mandatory for cell survival. In bacteria, this activity depends on the collaboration between the DnaK system and ClpB, which in vivo occurs in a highly crowded environment. The reactivation reaction includes two steps: extract...

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Hlavní autoři: Martín, Ianire, Celaya, Garbiñe, Alfonso, Carlos, Moro, Fernando, Rivas, Germán, Muga, Arturo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017315/
https://ncbi.nlm.nih.gov/pubmed/24806934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.03.042
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