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Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate

The chaperone ClpB in bacteria is responsible for the reactivation of aggregated proteins in collaboration with the DnaK system. Association of these chaperones at the aggregate surface stimulates ATP hydrolysis, which mediates substrate remodeling. However, a question that remains unanswered is whe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fernández-Higuero, Jose Angel, Aguado, Alejandra, Perales-Calvo, Judit, Moro, Fernando, Muga, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895705/
https://ncbi.nlm.nih.gov/pubmed/29643454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24140-5
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