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Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate

The chaperone ClpB in bacteria is responsible for the reactivation of aggregated proteins in collaboration with the DnaK system. Association of these chaperones at the aggregate surface stimulates ATP hydrolysis, which mediates substrate remodeling. However, a question that remains unanswered is whe...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Fernández-Higuero, Jose Angel, Aguado, Alejandra, Perales-Calvo, Judit, Moro, Fernando, Muga, Arturo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895705/
https://ncbi.nlm.nih.gov/pubmed/29643454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24140-5
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